
MOTS-C is a mitochondrial-derived peptide (MDP) made up of 16 amino acids and encoded within a short open reading frame of the mitochondrial genome, rather than nuclear DNA. Since its identification, it has become one of the more closely studied peptides in mitochondrial biology, largely because it appears to act as a signaling molecule between mitochondria and the rest of the cell. Helix Bio supplies MOTS-C as a lyophilized research peptide, manufactured to a purity standard of 99% or higher and tested in-house before every batch ships. It is sold exclusively for laboratory research use by qualified professionals — not for human or animal use, and not for human consumption.
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MOTS-C belongs to a small family of mitochondrial-derived peptides discovered through analysis of short open reading frames within mitochondrial DNA that were previously assumed to be non-coding. Researchers have since studied MOTS-C for its apparent role in retrograde signaling — communication that runs from the mitochondria back to the nucleus — and its interaction with cellular energy pathways, most notably AMPK. Because of this, MOTS-C shows up frequently in published research on metabolic regulation, insulin sensitivity, and exercise physiology models.
Helix Bio's MOTS-C is supplied as a sterile, lyophilized (freeze-dried) white to off-white powder, sealed in a single-use glass research vial. The peptide sequence is synthesized to match the naturally occurring MOTS-C sequence and is verified for identity and purity prior to release.
This product is intended for in-vitro and in-vivo laboratory research only. It is not formulated, packaged, or labeled for human or veterinary administration, and Helix Bio makes no claims regarding safety, efficacy, or outcomes outside of a controlled research setting.
Peptide purity and documentation vary widely across research-chemical suppliers, which makes sourcing one of the more time-consuming parts of setting up a study. Helix Bio addresses that by testing every MOTS-C batch through HPLC and mass spectrometry and making that data available as a Certificate of Analysis, so researchers can verify what they're working with before it reaches the bench. The peptide ships lyophilized in sealed, tamper-evident vials, which supports stability during transit and storage. Everything on the page — from the specifications table to the disclaimer below — is written to keep the product framed accurately as a research-use-only compound, not a consumer health product.
This product is not intended for individual consumers, and Helix Bio does not sell MOTS-C for personal, human, or veterinary use.
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