LL-37 is a cathelicidin-derived antimicrobial peptide supplied by Helix Bio for laboratory and academic research use only. It is not manufactured, labeled, or sold for human consumption, clinical use, or self-administration of any kind. Researchers working on innate immunity, antimicrobial resistance, wound-healing models, or skin barrier biology use LL-37 as a reference peptide, since it occurs naturally in human tissue and has been characterized in a large body of peer-reviewed literature. Helix Bio's LL-37 ships as a lyophilized powder, is verified through HPLC and mass spectrometry, and comes with a certificate of analysis for every batch. If you're looking for a research-grade LL-37 peptide vial with documented purity and consistent lot-to-lot quality, the sections below cover specifications, storage guidance, and the published research context researchers typically want before placing an order.
HPLC certified
Independent analysis
Highest standard
Full traceability
LL-37 is the only cathelicidin antimicrobial peptide identified in humans. It's generated by proteolytic cleavage of the C-terminal domain of hCAP18, the precursor protein encoded by the CAMP gene. The result is a linear, 37-residue peptide carrying a net positive charge that folds into an amphipathic alpha-helix when it contacts a lipid membrane — a structural feature that shows up repeatedly in the antimicrobial peptide literature.
LL-37 has been studied since the 1990s in contexts ranging from bacterial membrane disruption to immune cell chemotaxis, which is part of why it remains one of the more frequently requested host defense peptides in research settings.
Researchers typically request LL-37 for study designs involving:
LL-37 from Helix Bio is not sold, marketed, or intended for use as a supplement, drug, cosmetic ingredient, or any product for human or animal application.
When you're comparing LL-37 peptide suppliers, purity you can actually verify and consistency between batches are what matter most. Helix Bio tests each LL-37 lot with HPLC and mass spectrometry, then attaches the certificate of analysis to the order so the numbers aren't just a claim on a website.
The peptide ships lyophilized, which holds up better across transit and short-term storage than a pre-dissolved format. Combined with domestic USA manufacturing and shipping, that means shorter transit times and fewer temperature-exposure risks between the lab that makes it and the lab that uses it.
This product is not intended for individual consumers, self-administration, or any use outside a research setting.
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